Evidence-Based Palliative Care: Innovations in Pain Management and Quality of Life Improvement
Abstract
Palliative care has undergone significant transformation as global health systems respond to increasing rates of chronic and life-limiting illnesses. Persistent challenges in pain management, symptom control, and psychosocial support highlight the nemerging evidence-based approaches in palliative pain management and evaluate their impact on improving holistic well-being for patients receiving palliative care. A systematic review methodology weed for evidence-based innovations that enhance patient quality of life. This study aims to examine as employed, synthesizing findings from clinical trials, observational studies, and multidisciplinary intervention reports published over the past decade. The results indicate that multimodal pain management strategies—combining pharmacological optimization, non-pharmacological therapies, and digital monitoring technologies—significantly reduce pain severity and enhance patient comfort. The evidence further demonstrates that integrative interventions, such as mindfulness-based therapies, personalized care planning, and family-centered support models, contribute meaningfully to psychological resilience and perceived quality of life. The study concludes that evidence-based innovations in palliative care provide measurable benefits across physical, emotional, and social dimensions, underscoring the importance of adopting interdisciplinary and patient-centered approaches. Continued refinement of these strategies is essential for meeting the growing and complex needs of palliative care populations.
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References
Abby Philips, C. A., & Kedarisetty, C. K. (2023). Palliative Care for Patients with End-Stage Liver Disease. Journal of Clinical and Experimental Hepatology, 13(2), 319–328. Scopus. https://doi.org/10.1016/j.jceh.2022.08.003
Aregay, A., O’Connor, M., Stow, J., Ayers, N., & Lee, S. (2023). Palliative care in Ethiopia’s rural and regional health care settings: A qualitative study of enabling factors and implementation challenges. BMC Palliative Care, 22(1). Scopus. https://doi.org/10.1186/s12904-023-01283-5
Bandini, J. I., Schulson, L. B., Messan Setodji, C., Williams, J., Ast, K., & Ahluwalia, S. C. (2023). “palliative Care Is the only Medical Field That i Feel Like I’m Treated As a Person, Not As a Black Person”: A Mixed-Methods Study of Minoritized Patient Experiences with Palliative Care. Journal of Palliative Medicine, 26(2), 220–227. Scopus. https://doi.org/10.1089/jpm.2022.0237
Blumenthaler, A. N., Bruera, E., & Badgwell, B. (2023). Palliative and Supportive Care Consultation for Patients With Malignant Gastrointestinal Obstruction is Associated With Broad Interdisciplinary Management. Annals of Surgery, 277(2), 284–290. Scopus. https://doi.org/10.1097/SLA.0000000000004974
Butala, A. A., Buckingham, L., & Taunk, N. K. (2023). Palliative radiotherapy for gynecologic malignancies. In Palliative Radiation Oncology (pp. 179–192). Elsevier; Scopus. https://doi.org/10.1016/B978-0-323-87688-9.00025-8
Bužgová, R., Kozáková, R., & Bar, M. (2023). Pain, physical symptoms and functional assessment in progressive neurological disease in palliative care. BMJ Supportive and Palliative Care, 13(e1), E136–E143. Scopus. https://doi.org/10.1136/bmjspcare-2020-002416
Cimino, V., Chisari, C. G., Toscano, S., & Pattí, F. (2023). Palliative care in multiple sclerosis. In 36599504, Handb. Clin. Neurol. (Vol. 191, pp. 129–138). Elsevier B.V.; Scopus. https://doi.org/10.1016/B978-0-12-824535-4.00009-4
Corona, A., Dominguez, M., & Eti, S. (2023). Palliative Care in Kidney and Liver Diseases. Advances in Kidney Disease and Health, 30(4), 387–395. Scopus. https://doi.org/10.1053/j.akdh.2023.07.003
Cortezzo, D. E., & Carter, B. S. (2023). Palliative Care. In Avery’s Diseases of the Newborn (pp. 279-286.e4). Elsevier; Scopus. https://doi.org/10.1016/B978-0-323-82823-9.00023-4
Garcia, A. C. M., Isidoro, G. M., Paiva, E. M. D. C., Silva, A. E., Costa, I. C. P., & Bornemann-Cimenti, H. (2023). Palliative Sedation at Home: A Scoping Review. American Journal of Hospice and Palliative Medicine, 40(2), 173–182. Scopus. https://doi.org/10.1177/10499091221096412
Hoeltgen, L., Meixner, E., Hoegen-Sassmannshausen, P., Sandrini, E., Weykamp, F., Forster, T., Vinsensia, M., Lang, K., König, L., Arians, N., Fremd, C., Michel, L. L., Smetanay, K., Schneeweiß, A., Wallwiener, M., Debus, J., & Hörner-Rieber, J. (2023). Palliative Radiotherapy for Symptomatic Locally Advanced Breast Cancer. Technology in Cancer Research and Treatment, 22. Scopus. https://doi.org/10.1177/15330338231164537
Koekkoek, J. A. F., van der Meer, P. B., Pace, A., Hertler, C., Harrison, R., Leeper, H. E., Forst, D. A., Jalali, R., Oliver, K., Philip, J., Taphoorn, M. J. B., Dirven, L., & Walbert, T. (2023). Palliative care and end-of-life care in adults with malignant brain tumors. Neuro-Oncology, 25(3), 447–456. Scopus. https://doi.org/10.1093/neuonc/noac216
Loscos, A., & Marignac, G. (2023). Palliative care for dogs and cats in France: A qualitative and descriptive study based on professionals of the field. Ethics, Medicine and Public Health, 31. Scopus. https://doi.org/10.1016/j.jemep.2023.100953
Michel-Dhaine, C., Gautier-Leroy, L., Guinebert, F., & Chaboche, A. (2023). Pain management in 2023. Soins: La Revue de Reference Infirmiere, 68(877), 20–23. Scopus. https://doi.org/10.1016/j.soin.2023.06.007
Miranda-Chavez, B., Cruz-Chagua, R., & Taype-Rondán, A. (2023). Palliative care: Definition, importance and advances in Peru. Revista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo, 16(2). Scopus. https://doi.org/10.35434/rcmhnaaa.2023.162.1839
Neto, J., Casimiro, H. J., & Reis-Pina, P. (2023). Palliative Extubation in Pediatric Patients in the Intensive Care Unit and at Home: A Scoping Review. International Journal of Pediatrics (United Kingdom), 2023. Scopus. https://doi.org/10.1155/2023/6697347
Ortega-Chen, C., van Buren, N., Kwack, J., Mariano, J. D., Wang, S. E., Raman, C., & Cipta, A. (2023). Palliative Extubation: A Discussion of Practices and Considerations. Journal of Pain and Symptom Management, 66(2), e219–e231. Scopus. https://doi.org/10.1016/j.jpainsymman.2023.03.011
Özçelik, H., & Y?ld?r?m, D. (2023). Palliative care. In Med. Nurs. (pp. 531–536). Nova Science Publishers, Inc.; Scopus. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178208309&partnerID=40&md5=00c20f136026c23d17533a16e5eb574f
Ramani, V. K., Jayanna, K., & Naik, R. (2023). A commentary on cancer prevention and control in India: Priorities for realizing SDGs. Health Science Reports, 6(2). Scopus. https://doi.org/10.1002/hsr2.1126
Regis, J. M., de Menezes Nunes, A. V., Brito, L. F. S., Melo, M. B. M., da Conceição, M. V., de Castro Vasconcelos, M. C., de Mattos, R. M. P. R., & Pimentel, D. (2023). Palliative care in an active teaching methodology. Revista Bioetica, 31(2). Scopus. https://doi.org/10.1590/1983-803420232489PT
Rettobyaan, F., & Widodo, B. (2023). Palliative management of a patient with gastric outlet obstruction (GOO) due to caput pancreatic cancer during COVID-19 pandemic. Bali Medical Journal, 12(1), 744–748. Scopus. https://doi.org/10.15562/bmj.v12i1.4118
Rodríguez-Gómez, M., Ruíz-Pérez, I., Escribá-Agüir, V., Pastor-Moreno, G., & Henares-Montiel, J. (2023). Palliative care and social inequalities in cancer. A narrative literature review. Medicina Paliativa, 30(2), 95–101. Scopus. https://doi.org/10.20986/medpal.2022.1358/2022
Roydhouse, J., Connolly, A., Daveson, B., de Graaff, B., Blanchard, M., & Currow, D. C. (2023). Palliative care symptoms and problems in a culturally and linguistically diverse population: Large retrospective cohort study. BMJ Supportive and Palliative Care, 13(e3), E1228–E1237. Scopus. https://doi.org/10.1136/spcare-2022-004111
Schutz, R. E. C., & Creutzfeldt, C. J. (2023). Palliative care after stroke survival. In 36599514, Handb. Clin. Neurol. (Vol. 191, pp. 3–11). Elsevier B.V.; Scopus. https://doi.org/10.1016/B978-0-12-824535-4.00003-3
Sneider, A. P., Dhiman, A., Sood, D., Ong, C., Tun, S., Malec, M., Levine, S., Turaga, K. K., & Eng, O. S. (2023). Palliative Care and Characterization of Symptoms in Patients Undergoing Cytoreductive Surgery/Hyperthermic Intraperitoneal Chemotherapy. Journal of Surgical Research, 283, 1154–1160. Scopus. https://doi.org/10.1016/j.jss.2022.11.061
Spary-Kainz, U., Posch, N., Paier-Abuzahra, M., Lieb, M., Avian, A., Zelko, E., & Siebenhofer, A. (2023). Palliative Care Survey: Awareness, Knowledge and Views of the Styrian Population in Austria. Healthcare (Switzerland), 11(19). Scopus. https://doi.org/10.3390/healthcare11192611
Tuffnell, R., Sayers, P., Davis, E., Chan, E., Burkin, J., Moffat, C., Traub, C., Sheldon, M., Booth, S., & Spathis, A. (2023). Palliative care symptom management expertise for long-COVID. BMJ Supportive and Palliative Care, 13(1), 61–62. Scopus. https://doi.org/10.1136/spcare-2022-004032
Volberg, C., Wulf, H., & Schubert, A.-K. (2023). Pain Management in Palliative Care. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie?: AINS, 58(2), 95–110. Scopus. https://doi.org/10.1055/a-1962-6298