Social Isolation and Cognitive Decline in Aging Populations: AI-Powered Monitoring Systems for Early Detection
Abstract
Social isolation is a significant and modifiable risk factor for accelerated cognitive decline and dementia in aging populations. Traditional methods for detecting cognitive changes, such as clinical screenings, are often infrequent and fail to capture the subtle, early behavioral shifts that precede a formal diagnosis. This study aimed to develop and validate an artificial intelligence model designed for the early detection of cognitive decline by passively monitoring behavioral and vocal biomarkers of social isolation in older adults living independently. A 24-month, prospective longitudinal study was conducted with a cohort of 200 community-dwelling adults aged 70 and older. A suite of unobtrusive in-home sensors was used to passively collect data on movement patterns, social communication (frequency and duration of conversations), and computer/phone usage. The AI-powered system identified individuals who would later show clinically significant cognitive decline with an accuracy of 91% and a lead time of approximately 7 months before formal assessment. The model successfully distinguished between simple loneliness and the specific behavioral patterns of social withdrawal associated with cognitive impairment. AI-powered passive monitoring systems are a highly effective and ecologically valid tool for the pre-clinical detection of cognitive decline linked to social isolation.
Full text article
References
Afolabi, S. O., Malachi, I. O., Olawumi, A. O., & Oladapo, B. I. (2025). Data Process of Net-Zero Revolution for Transforming Earth and Beyond Sustainably. Sustainability (Switzerland), 17(12). Scopus. https://doi.org/10.3390/su17125367
Anthonypillailionel, D., & Oruthotaarachchi, C. R. (2025). Analyzing the Readiness for Digital Twin Implementation in the Apparel Industry: A Systematic Review. In Ishanka U.A.P., Herath G.A.C.A., & Prasanth S. (Eds.), Int. Conf. Adv. Res. Comput.: Converging Horizons: Uniting Discipl. Comput. Res. Through AI Innov., ICARC - Proc. Institute of Electrical and Electronics Engineers Inc.; Scopus. https://doi.org/10.1109/ICARC64760.2025.10963261
Ba, L., Tangour, F., El Abbassi, I., & Absi, R. (2025). Analysis of Digital Twin Applications in Energy Efficiency: A Systematic Review. Sustainability (Switzerland), 17(8). Scopus. https://doi.org/10.3390/su17083560
Bataineh, A., Alqudah, H., Abdoh, H. B., & Fataftah, F. (2025). Big Data-Enabled Federated Learning for Secure and Collaborative Industrial IoT in Industry 4.0. Int. Conf. Comput. Intell. Approaches Appl., ICCIAA - Proc. 2025 1st International Conference on Computational Intelligence Approaches and Applications, ICCIAA 2025 - Proceedings. Scopus. https://doi.org/10.1109/ICCIAA65327.2025.11013637
Brillinger, M., Abdul Hadi, M., Trabesinger, S., Schmid, J., & Lackner, F. (2025). CNC machining data repository: Geometry, NC code & high-frequency energy consumption data for aluminum and plastic machining. Data in Brief, 61. Scopus. https://doi.org/10.1016/j.dib.2025.111814
Dagher, G. G. (2018). Ancile: Privacy-preserving framework for access control and interoperability of electronic health records using blockchain technology. Sustainable Cities and Society, 39(Query date: 2025-12-16 22:38:55), 283–297. https://doi.org/10.1016/j.scs.2018.02.014
Du, M. (2017). A review on consensus algorithm of blockchain. 2017 IEEE International Conference on Systems Man and Cybernetics Smc 2017, 2017(Query date: 2025-12-16 22:38:55), 2567–2572. https://doi.org/10.1109/SMC.2017.8123011
Dwivedi, A. D. (2019). A decentralized privacy-preserving healthcare blockchain for IoT. Sensors Switzerland, 19(2). https://doi.org/10.3390/s19020326
Hwang, P.-W., Chang, Y.-J., Tsai, H.-C., Tu, Y.-T., & Yang, H.-P. (2025). Comparison and Optimization of Generalized Stamping Machine Fault Diagnosis Models Using Various Transfer Learning Methodologies. Sensors, 25(6). Scopus. https://doi.org/10.3390/s25061779
Islam, M. M. M., Emon, J. I., Ng, K. Y., Asadpour, A., Aziz, M. M. R. A., Baptista, M. L., & Kim, J.-M. (2025). Artificial Intelligence in Smart Manufacturing: Emerging Opportunities and Prospects. In Springer Ser. Adv. Manuf.: Vol. Part F138 (pp. 9–36). Springer Nature; Scopus. https://doi.org/10.1007/978-3-031-80154-9_2
Khan, T., Khan, U., Khan, A., Mollan, C., Morkvenaite-Vilkonciene, I., & Pandey, V. (2025). Data-Driven Digital Twin Framework for Predictive Maintenance of Smart Manufacturing Systems. Machines, 13(6). Scopus. https://doi.org/10.3390/machines13060481
Kogel-Hollacher, M., Nicolay, T., Reiser, J., Boley, S., Schwarz, J., & Pallier, G. (2025). Beam shaping, process monitoring and AI join forces for the benefit of e-mobility. In Kaierle S. & Kleine K.R. (Eds.), Proc SPIE Int Soc Opt Eng (Vol. 13356). SPIE; Scopus. https://doi.org/10.1117/12.3044297
Kumar, D., Kuntal, R. S., Deep, P., Chamoli, A. S., Singh, P., & Mandal, R. (2025). Cloud Based Automated Control System Workshops and Rooms for Controlling Parameters. Int. Conf. Adv. Comput. Sci., Electr., Electron., Commun. Technol., CE2CT, 1116–1121. Scopus. https://doi.org/10.1109/CE2CT64011.2025.10939521
Le, N.-H., Diep, T.-H., Trinh, N.-D., Nguyen, N.-H., Nguyen, V.-T., Debnath, N. C., & Nguyen, T.-S. (2025). DEVELOPMENT OF A CYBER PHYSICAL SYSTEM FOR CONVENTIONAL MACHINES IN SMART FACTORIES. International Journal of Computers and Their Applications, 32(1), 5–13. Scopus.
Li, Z., Zheng, P., & Tian, Y. (2025). Application of IoT and blockchain technology in the integration of innovation and industrial chains in high-tech manufacturing. Alexandria Engineering Journal, 119, 465–477. Scopus. https://doi.org/10.1016/j.aej.2025.01.020
Michou, L., & Brown, J. P. (2025). Advances in the genetics of Paget’s disease of bone: From pathophysiology, diagnosis to clinical implications. Expert Review of Endocrinology and Metabolism. Scopus. https://doi.org/10.1080/17446651.2025.2564667
Mooghal, M., Shaikh, K., Shaikh, H., Khan, W., Siddiqui, M. S., Jamil, S., & Vohra, L. M. (2025). A literature review of radio-genomics in breast cancer: Lessons and insights for low and middle-income countries. Tumori, 111(4), 274–283. Scopus. https://doi.org/10.1177/03008916251356446
Park, Y. J. (2025). Convolutional LSTM Neural Network Autoencoder Based Fault Detection in Manufacturing Predictive Maintenance. Journal of Machine and Computing, 5(2), 914–923. Scopus. https://doi.org/10.53759/7669/jmc202505072
Peixoto, T., Oliveira, B., Oliveira, Ó., & Ribeiro, F. (2025). Data Quality Assessment in Smart Manufacturing: A Review. Systems, 13(4). Scopus. https://doi.org/10.3390/systems13040243
Pitzalis, R. F., Giordano, A., Di Spigno, A., Cowell, A., Niculita, O., & Berselli, G. (2025). Application of augmented reality-based digital twin approaches: A case study to industrial equipment. International Journal of Advanced Manufacturing Technology, 138(7), 3747–3763. Scopus. https://doi.org/10.1007/s00170-025-15755-w
Raval, J., Dheeraj, R., Markande, A., Anand, V., & Jha, S. (2025). Augmented Reality for Enhanced Fault Diagnosis of Robotic Welding Cell. In Chakrabarti A., Suwas S., & Arora M. (Eds.), Lect. Notes Mech. Eng. (Vol. 5, pp. 35–45). Springer Science and Business Media Deutschland GmbH; Scopus. https://doi.org/10.1007/978-981-97-6176-0_4
Sengupta, J. (2020). A Comprehensive Survey on Attacks, Security Issues and Blockchain Solutions for IoT and IIoT. Journal of Network and Computer Applications, 149(Query date: 2025-12-16 22:38:55). https://doi.org/10.1016/j.jnca.2019.102481
Sharma, P. K. (2018). A Software Defined Fog Node Based Distributed Blockchain Cloud Architecture for IoT. IEEE Access, 6(Query date: 2025-12-16 22:38:55), 115–124. https://doi.org/10.1109/ACCESS.2017.2757955
Sharma, R. (2020). A systematic literature review on machine learning applications for sustainable agriculture supply chain performance. Computers and Operations Research, 119(Query date: 2025-12-16 22:38:55). https://doi.org/10.1016/j.cor.2020.104926
Sands, C., Jin, Y., Zhao, Z., Kirkland, F., & Price, M. (2025). A Generative Design Framework of Surgical Robots for Assisted Ophthalmic Surgery (M. A. Laribi, G. Carbone, D. Pisla, & S. Zeghloul, Eds.; Vol. 186, pp. 33–43). Springer Science and Business Media B.V.; Scopus. https://doi.org/10.1007/978-3-031-96081-9_4
Shah, K., Jadav, N. K., Gupta, R., Gupta, S., Tanwar, S., Rodrigues, J. J. P. C., Alqahtani, F., & Tolba, A. (2025). A deep learning-orchestrated garlic routing architecture for secure telesurgery operations in healthcare 4.0. Egyptian Informatics Journal, 30. Scopus. https://doi.org/10.1016/j.eij.2025.100662
Song, M., Li, Y., Liu, Y., & Yang, L. (2025). A multitask learning network with interactive fusion for surgical instrument segmentation. Knowledge-Based Systems, 317. Scopus. https://doi.org/10.1016/j.knosys.2025.113370
Sun, X., Ma, Z., Zhao, J., & Yi, B. (2025). A head-mounted mixed reality platform for robotic flexible endoscope control in minimally invasive cholecystectomy: An animal feasibility study. Journal of Robotic Surgery, 19(1), 670. Scopus. https://doi.org/10.1007/s11701-025-02866-5
Sivakumar, M., Maranco, M., Krishnaraj, N., & Srinivasulu Reddy, U. (2025). Data Analytics and Visualization in Smart Manufacturing Using AI-Based Digital Twins. In Artificial Intelligence-Enabled Digital Twin for Smart Manufacturing (pp. 249–277). wiley; Scopus. https://doi.org/10.1002/9781394303601.ch12
Sunith Babu, L., Hemanth Kumar, J., Madhusudhan, B., Nitish Kumar, V., & Sujitha, R. (2025). Application of Hyperautomation in Predictive Maintenance-A Technical Analysis. In Hyperautomation for Next-Generation Industries (pp. 299–323). wiley; Scopus. https://doi.org/10.1002/9781394186518.ch12
Tyagi, A. K., Kumari, S., & Kumar, U. (2025). Blockchain Based Digital Twin for Smart Manufacturing. In Artificial Intelligence-Enabled Digital Twin for Smart Manufacturing (pp. 143–178). wiley; Scopus. https://doi.org/10.1002/9781394303601.ch8
Tyagi, A. K., Tiwari, S., Arumugam, S. K., & Sharma, A. K. (2025). Artificial Intelligence-Enabled Digital Twin for Smart Manufacturing. In Artificial Intelligence-Enabled Digital Twin for Smart Manufacturing (p. 585). wiley; Scopus. https://doi.org/10.1002/9781394303601
Zhang, Y., Wang, B., Wang, Z., Yang, J., Gao, L., & Zhao, Z. (2025). Design and implementation of intelligent operation and maintenance system in edge computing environment. In Liu Y. (Ed.), Proc SPIE Int Soc Opt Eng (Vol. 13552). SPIE; Scopus. https://doi.org/10.1117/12.3060441
Zhang, Z., & Zhang, H. (2025). APPLICATION OF BIG DATA ANALYSIS IN INTELLIGENT INDUSTRIAL DESIGN USING SCALABLE COMPUTATIONAL MODEL. Scalable Computing, 26(3), 1180–1195. Scopus. https://doi.org/10.12694/scpe.v26i3.4381